[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Journal Information::
Editorial Policies::
Articles archive::
For Authors::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Contact Us
:: Volume 17, Issue 2 (Foll Text in Persian 2005) ::
J Iran Dent Assoc 2005, 17(2): 62-67 Back to browse issues page
Evaluation of clinical and histological parameters in patients with oral squamous cell carcinoma referred to Tehran Faculty of Dentistry (1966 – 2002)
Nosrat ollah Eshghyar * 1, Poriya Motahari , Azam Khorshidian
1- , eshghyar@tums.ac.ir
Abstract:   (13482 Views)

Evaluation of clinical and histological parameters in patients with oral squamous cell carcinoma referred to Tehran Faculty of Dentistry (1966 – 2002)

Dr. N. Eshghyar* - Dr. P. Motahari** - Dr. A. Khorshidian***

*- Associate Professor of Oral & Maxillofacial Pathology Dept.- Faculty of Dentistry-Tehran University of Medical Sciences.

**-Assistant Professor of Oral & Maxillofacial Pathology Dept.-Faculty of Dentistry-Tehran University of Medical Sciences.

*** - Dentist.

Background and Aim: Squamous cell carcinoma (SCC) is the most prevalent neoplasm in oral cavity and due to the numerous complications arising from lesions or treatment and its high mortality rate has been paid too much attention. The goal of the present study was to evaluate clinical and histological parameters in patients with SCC referred to Pathology department, Dentistry Faculty, Tehran University of Medical Sciences.

Materials and Methods: In this case series study, clinical and histological information of 271 patients affected with SCC were collected through the evaluation of all documents in pathology department from 1966 to 2002. All surgical documents and histological slides were studied and analyzed using SPSS version 11.0 X2 test and t test.

Results: Malignancy score was higher in males than females. The maximum, minimum and average age of patients were 85, 19 and 56.73 years, respectively. The majority of lesions were observed during the sixth decade of life and the ratio of males to females was 5:4. Malignancy score, in young patients, was higher than old ones. The most common site for lesions was mandibular ridge and the least common was the upper lip. Lesions of maxillary sinus and soft palate had the highest and lesions of the upper lip had the lowest malignancy score. 74% of the patients were smokers. Most of the lesions showed high keratinization, slight inflammation and polymorphism and were of grade I.

Conclusion: SCC incidence is more common among males compared to females. Patients older than 50 years are considered as the high risk group for this neoplasm. Mandibular ridge is the most common site. Majority of the lesions are well differentiated in oral cavity. Malignancy score is higher in males and young patients than females and old patients.

Key words: Squamous cell carcinoma – Grading – Polymorphism.

Keywords: Squamous cell carcinoma, Grading, Polymorphism
Full-Text [PDF 153 kb]   (3095 Downloads)    
Type of Study: Research | Subject: General
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Eshghyar N O, Motahari P, Khorshidian A. Evaluation of clinical and histological parameters in patients with oral squamous cell carcinoma referred to Tehran Faculty of Dentistry (1966 – 2002). J Iran Dent Assoc 2005; 17 (2) :62-67
URL: http://jida.ir/article-1-165-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 17, Issue 2 (Foll Text in Persian 2005) Back to browse issues page
Journal of Iranian Dental Association

AWT IMAGE

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Persian site map - English site map - Created in 0.06 seconds with 37 queries by YEKTAWEB 4645