Comparison of the Analgesic Efficacy of Odontopaste Ò and a Compound with Similar Formulation as Intracanal Medicaments
Dr. Eftekhar B .,1 Dr. Moghimipour E.,2 Dr. Pourakbar Jahandideh P., 3 Dr. Ahmadi K. 4
1 Assistant Professor, Department of Endodontics, School of Dentistry, Ahvaz Jundi Shapur University of Medical Sciences. Ahvaz , Iran. 2 Associate Professor, Department of Pharmaceutics , School of Pharmacy, Ahvaz Jundi Shapur University of Medical Sciences. Ahvaz , Iran . 3 Endodontist . 4 PhD of Biostatistics, Department of Biostatistician of Health, School of Medicine , Ahvaz Jundi Shapur University of Medical Sciences. Ahvaz , Iran.
(Received 20 Nov, 2012 Accepted 23 July, 2013)
Background and Aim : Different medicaments are used for pain reduction following an emergency endodontic treatment. The aim of this randomized controlled clinical trial was to evaluate the analgesic efficacy of Odontopaste® and a corticosteroid-containing compound used as intracanal medicaments in between root canal therapy (RCT) appointments .
Materials and Methods : In this randomized controlled clinical trial, 120 lower first and second mandibular molars with spontaneous pain and sensitivity to percussion were selected and divided into three groups of 40. After root canal preparation, patients were randomly assigned to one of the three groups. Root canals were dressed with Odontopaste in group 1, with an intracanal medicament in group 2 and with placebo in group 3. Patients determined their degree of pain intensity and percussion sensitivity on a Heft-Parker VAS diagram before the first appointment and 24 hours and 7 days post-treatment.
Data were analyzed using ANOVA, Tukey’s test and Welch test .
Results : The mean spontaneous pain and percussion sensitivity scores at 24 hours after the first appointment in groups 1 and 2 were significantly lower than in group 3 (P<0.001). No statistically significant difference was found between the groups after 7 days neither in spontaneous pain nor in percussion sensitivity .
Conclusion : Odontopaste® and the intracanal medicament caused a statistically significant reduction in postoperative
pain and percussion sensitivity at 24 hours but there was no statistically significant difference at 7 days with the placebo .
Key words : Anti-inflammatory agent, Clindamycin hydrochloride, Periapical periodontitis, Root canal medicament, Triamcinolone acetonide
Corresponding Author: Dr. Pourakbar Jahandideh P , Endodontist .