Effects of Casein Phosphopeptide Amorphous Calcium Phosphate and Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride on  Alterations of Dental Plaque PH Following Sucrose Consumption

Heshmat , Haleh; Banava , Sepideh; Abdian , Hadi; Kharrazi Fard , Mohammad Javad

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Volume 26, Issue 4 (10-2014)

J Iran Dent Assoc 2014, 26(4): 274-279

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Effects of Casein Phosphopeptide Amorphous Calcium Phosphate and Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride on Alterations of Dental Plaque PH Following Sucrose Consumption

Haleh Heshmat ^*

¹, Sepideh Banava²

, Hadi Abdian³

, Mohammad Javad Kharrazi Fard⁴

1- Assistant Professor, Department of Operative Dentistry, School of Dentistry, Islamic Azad University. Dental Branch, Tehran, Iran , H_heshmat@dentaliau.ac.ir
2- Assistant Professor, Department of Operative Dentistry, School of Dentistry, Islamic Azad University. Dental Branch, Tehran, Iran
3- Dentist
4- Research Member of Dental Research Center Tehran University of Medical Sciences. Tehran, Iran

Abstract: (4076 Views)

Background and Aim: Plaque pH drop after consumption of sugary materials may dis-solve enamel minerals. Casein phosphopeptide amorphous calcium phosphate (CPP-ACP) is a paste enriched with calcium and phosphate. The new formulation of this paste, casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACPF), contains 900 ppm fluoride. This paste can neutralize the low pH of bacterial plaque. This study compares the efficacy of CPP-ACP and CPP-ACPF for neutralizing plaque acidity at different time points.

Materials and Methods: This clinical trial was conducted on 40 students. Plaque pH at the distal of first molar was measured before and 10 minutes after the consumption of 10% sucrose solution. In the next step, CPP-ACP and CPP-ACPF pastes were applied as recommended by the manufacturers to the tooth surface. Plaque pH was measured at 30 minutes, 60 minutes and 24, 48, 72 and 96 hours. Data was recorded and analyzed by repeated measures ANOVA (p<0.05).

Results: Both CPP-ACP and CPP-ACPF increased plaque pH similarly in the first 48 hours. However, the pattern changed from this time point on.

Conclusion: CPP-ACP and CPP-ACPF had similar efficacy for up to 48 hours, but CPP- ACPF was capable of keeping the pH high by up to 96 hours.

Keywords: CPP-ACP, CPP-ACPF, Plaque pH, Demineralization

Full-Text [PDF 158 kb] (2071 Downloads)

Type of Study: Original | Subject: Restorative Dentistry

References

1. Heymann H O, Swift Jr, Ritter AV. Sturdevant’s art and science of operative dentistry. 6th ed. Canada: Elsevier; 2012, 48-60,70.

2. Kitasako Y, Cochrane NJ, Khairul M, Shida K, Adams GG, Burrow MF, Reynolds EC, Tagami J. The clinical application of surface pH measurements to longitudinally assess white spot enamel lesions. J Dent. 2010 Jul; 38(7):584-90.

3. Caruana PC, Mulaify SA, Moazzez R, Bartlett D. The effect of casein and calcium containing paste on plaque pH following a subsequent carbohydrate challenge. J Dent. 2009 Jul; 37(7): 522-6.

4. Winston AE, Bhaskar SN. Caries prevention in the 21st century. J Am Dent Assoc. 1998 Nov; 129 (11):1579-87.

5. Featherstone JD. The science and practice of caries prevention. J Am Dent Assoc. 2000 Jul; 131 (7):887-99.

6. Fejerskov O, Kidd E.Dental caries the disease and its clinical management. 2th ed. Oxford, UK: Blackwell; 2008, 182-3.

7. Jensen ME, Wefel JS. Effects of processed cheese on human plaque pH and demineraliza-tion and remineralization. Am J Dent. 1990 Oct; 3(5): 217-23.

8. Heshmat H, Banava S, Mohammadi E, Kharazifard MJ, Mojtahedzadeh F. The effect of recommending a CPP-ACPF product on sali-vary and plaque pH levels in orthodontic pa-tients: A randomized cross-over clinical trial. Acta Odontol Scand. 2014 Nov; 72(8):903-7.

9. Borges BC, de Souza Borges J, de Araujo LS, Machado CT, Dos Santos AJ, de Assunçao Pinheiro IV. Update on nonsurgical, ultraconservative approaches to treat effectively non-cavitated caries lesions in permanent teeth. Eur J Dent. 2011 Apr;5(2):229-36.

10. Newman M, Henry H. Takei H, Perry R. Klokkevold P, Carranza A. Carranza’s clinical periodontology. 10thed; St. Louis: Saunders. 2006, 50:783.

11. Koparal E, Eronat C, Eronat N. In vivo assessment of dental plaque pH changes in children after ingestion of snack foods. ASDC J Dent Child. 1998 Nov-Dec;65(6):478-83, 438-9.

12. Axelsson Per. Diagnosis and risk prediction dental caries. 1th ed. Illinoise, USA: Quintes-sence; 2000, 55-76, 218-224.

13. Kaste LM, Selwitz RH, Oldakowski RJ, Brunelle JA, Winn DM, Brown LJ. Coronal car-ies in the primary and permanent dentition of children and adolescents 1-17 years of age: United States, 1988-1991. J Dent Res. 1996 Feb;75 Spec No: 631-41.

14. Fejerskov O, Kidd E. Dental caries the disease and its clinical management. 2th ed. Oxford, UK: Blackwell; 2008, 196-200.

15. Hay DI. Salivary factors in caries models. Adv Dent Res. 1995 Nov;9(3):239-43.

16. 16. Srinivasan N, Kavitha M, Loganathan SC. Comparison of the remineralization potential of CPP-ACP and CPP-ACP with 900 ppm fluoride on eroded human enamel: An in situ study. Arch Oral Biol. 2010 Jul;55(7):541-4.

17. Reynolds EC. Calcium phosphate-based remineralization systems: Scientific evidence. Aust Dent J. 2008 Sept; 53(3):268-73.

18. Johansson AK, Lingstrom P, Birkhed D. Camparison of factore potentially related to the occurrence of dental erosion in high and low- erosion groups. Eur J Oral Sci. 2002 Jun; 110(3): 204-11.

19. Cochrance NJ, Cai F, Hug NL, Burrow MF, Reynolds EC. New Approaches to remineraliza-tion of tooth enamel. J Dent Res. 2010 Nov; 89(11): 1187-1197.

20. Ogata K, Warita S, Shimazu K, Kawakami T, Aoyagi K, Karibe H. Combined effect of paste containing casein phosphopeptide-amorphous calcium phosphate and fluoride on enamel le-sions: an in vitro pH-cycling study. Pediatr Dent. 2010 Sept-Oct;32(5):433-8.

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Heshmat H, Banava S, Abdian H, Kharrazi Fard M J. Effects of Casein Phosphopeptide Amorphous Calcium Phosphate and Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride on Alterations of Dental Plaque PH Following Sucrose Consumption. J Iran Dent Assoc 2014; 26 (4) :274-279
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Volume 26, Issue 4 (10-2014)

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