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:: Volume 30, Issue 2 (4-2018) ::
J Iran Dent Assoc 2018, 30(2): 58-65 Back to browse issues page
Evaluation of the Association Between Maternal Periodontal Health and Preeclampsia
Roya Shariatmadar Ahmadi1 , Arefe Lor2 , Ferena Sayar3 , Maryam Kashanian4 , Samira Hajisadeghi * 5
1- Assistant Professor, Department of Periodontology, Dental Branch, Islamic Azad University, Tehran, Iran
2- Dentist, Private Office, Tehran, Iran
3- Associate Professor, Department of Periodontology, Dental Branch, Islamic Azad University, Tehran, Iran
4- Professor, Department of Obstetrics and Gynecology, Akbarabadi Teaching Hospital, Tehran University of Medical Sciences, Teh-ran, Iran
5- Assistant Professor, Dental and Oral Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Qom University of Medical Sciences, Qom, Iran , hajisadeghi@dnt.mui.ac.ir
Abstract:   (2593 Views)
Abstract Background and Aim: Preeclampsia is a considerable complication of pregnancy. Chronic inflammations such as periodontitis may lead to a transient low-grade bacteremia in the maternal-fetal circulation, inducing systemic immune responses, placental abnormalities, and other clinical manifestations of preeclampsia. There are inconsistent findings regarding the correlation between periodontitis and preeclampsia. The aim of this study was to compare periodontal parameters in preeclamptic and normotensive pregnant women.
Materials and Methods: This case-control study was conducted among pregnant women visiting Akbarabadi Teaching Hospital, Tehran, Iran, for specialized care during 2015-16. From among 260 pregnant women, 100 with gestational hypertension were selected as the case group, and 100 without gestational hypertension were recruited as the control group. The examined periodontal parameters included Probing Depth (PD), Clinical Attachment Loss (CAL), Bleeding on Probing (BOP), and Plaque Control Record (PCR). The participants' demographic data, prenatal history, and family history were collected through interviewing and assessing their medical records. Data were analyzed by Mann-Whitney U test.
Results: Although there were significant statistical differences between the groups with regards to the mean ± standard deviation (SD) of PD (P<0.0001), CAL (P<0.0001), PCR (P=0.001), and BOP (P=0.016) indices, yet the differences were clinically smaller than 0.3 mm and could not be measured with a periodontal probe. Also, the percentage of periodontal diseases was 98% in preeclamptic women and 93% in normotensive women (P=0.17).
Conclusion: The present study did not support the theory of the relationship between periodontal parameters and preeclampsia.
Keywords: Periodontal Diseases, Pre-Eclampsia, Pregnancy
Full-Text [PDF 377 kb]   (1122 Downloads)    
Type of Study: Original | Subject: Periodontology
References
1. Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases. Lancet. 2005 Nov 19; 366 (9499):1809-20.
2. Winning L, Linden GJ. Periodontitis and Systemic Disease: Association or Causality? Curr Oral Health Rep. 2017;4(1):1-7.
3. Xiong X, Buekens P, Vastardis S, Yu SM. Periodontal disease and pregnancy outcomes: state-of-the-science. Obstet Gynecol Surv. 2007 Sep;62(9):605-15.
4. Chen BA, Parviainen K, Jeyabalan A. Correlation of catheterized and clean catch urine protein/creatinine ratios in preeclampsia evaluation. Obstet Gynecol. 2008 Sep;112(3):606-10.
5. Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005 Feb 26-Mar 4;365 (9461):785-99.
6. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gy-necol. 2000 Jul;183(1):S1-S22.
7. Harmon AC, Cornelius DC, Amaral LM, Faulkner JL, Cunningham MW Jr, Wallace K, et al. The role of inflammation in the pathology of preeclampsia. Clin Sci (Lond). 2016 Mar; 130(6): 409-19.
8. Gibbs RS, Romero R, Hillier SL, Eschenbach DA, Sweet RL. A review of premature birth and subclinical infection. Am J Obstet Gynecol. 1992 May;166(5):1515-28.
9. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008 Jan 5;371(9606):75-84.
10. Loesche WJ, Grossman NS. Periodontal disease as a specific, albeit chronic, infection: diagnosis and treatment. Clin Microbiol Rev. 2001 Oct; 14(4):727-52.
11. Yaghini J, Mostajeran F, Afshari E, Naghsh N. Is periodontal disease related to preeclampsia? Dent Res J (Isfahan). 2012 Nov;9(6):770-3.
12. Moura da Silva G, Coutinho SB, Piscoya MD, Ximenes RA, Jamelli SR. Periodontitis as a risk factor for preeclampsia. J Periodontol. 2012 Nov; 83(11):1388-96.
13. Nabet C, Lelong N, Colombier ML, Sixou M, Musset AM, Goffinet F, et al. Maternal periodontitis and the causes of preterm birth: the case-control Epipap study. J Clin Periodon-tol. 2010 Jan; 37(1):37-45.
14. Sayar F, Hoseini MS, Abbaspour S. Effect of Periodontal Disease on Preeclampsia. Iran J Public Health. 2011;40(3):122-7.
15. Khader YS, Jibreal M, Al-Omiri M, Amarin Z. Lack of association between periodontal parameters and preeclampsia. J Periodontol. 2006 Oct; 77(10):1681-7.
16. Srinivas SK, Sammel MD, Stamillo DM, Clothier B, Jeffcoat MK, Parry S, et al. Perio-dontal disease and adverse pregnancy out-comes: is there an association? Am J Obstet Gynecol. 2009 May; 200(5):497.el-8.
17. Lohsoonthorn V, Kungsadalpipob K, Chanchareonsook P, Limpongsanurak S, Vanichjakvong O, Sutdhibhisal S, et al. Mater-nal periodontal disease and risk of preeclamp-sia: a case-control study. Am J Hypertens. 2009 Apr; 22 (4):457-63.
18. Lenox JA, Kopczyk RA. A clinical system for scoring a patient's oral hygiene performance. J Am Dent Assoc.1973 Apr;86(4):849-52.
19. O'Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol. 1972 Jan;43(1):38.
20. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975 Dec;25(4):229-35.
21. Silness J, Loe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand. 1964 Feb;22:121-35.
22. Tooher J, Thornton C, Makris A, Ogle R, Korda A, Hennessy A. All Hypertensive Disor-ders of Pregnancy Increase the Risk of Future Cardiovascular Disease. Hypertension. 2017 Oct; 70(4):798-803.
23. Bobetsis YA, Barros SP, Offenbacher S. Exploring the relationship between periodontal disease and pregnancy complications. J Am Dent Assoc. 2006 Oct;137 Suppl:7S-13S.
24. Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG. 2006 Feb;113(2):135-43.
25. Nagpal R, Yamashiro Y, Izumi Y. The Two-Way Association of Periodontal Infection with Systemic Disorders: An Overview. Media-tors Inflamm. 2015;2015:793898.
26. Sharma A, Ramesh A, Thomas B. Evaluation of plasma C-reactive protein levels in pregnant women with and without periodontal disease: A comparative study. J Indian Soc Periodontol. 2009 Sep;13(3):145-9.
27. Shetty MS, Ramesh A, Shetty PK, Agumbe P. Salivary and Serum Antioxidants in Women with Preeclampsia with or Without Periodontal Disease. J Obstet Gynaecol India. 2018 Feb;68(1):33-38.
28. Dahiya P, Kamal R, Gupta R, Saini H. Evaluation of the serum antioxidant status in patients with chronic periodontitis. Indian J Multidiscip Dent. 2016 Aug;6(1):3-6.
29. Durand R, Gunselman EL, Hodges JS, Diangelis AJ, Michalowicz BS. A pilot study of the association between cariogenic oral bacteria and preterm birth. Oral Dis. 2009 Sep;15(6):400-6.
30. Shetty M, Shetty PK, Ramesh A, Thomas B, Prabhu S, Rao A. Periodontal disease in preg-nancy is a risk factor for preeclampsia. Acta Obstet Gynecol Scand. 2010 May;89(5):718-21.
31. Desai K, Desai P, Duseja S, Kumar S, Mahendra J, Duseja S. Significance of maternal periodontal health in preeclampsia. J Int Soc Prev Community Dent. 2015 Mar-Apr;5(2):103-7.
32. Ha JE, Jun JK, Ko HJ, Paik DI, Bae KH. Association between periodontitis and preeclampsia in never-smokers: a prospective study. J Clin Periodontol. 2014 Sep;41(9):869-74.
33. Pattanashetti JI, Nagathan VM, Rao SM. Evaluation of Periodontitis as a Risk for Preterm Birth among Preeclamptic and Non–Preeclamptic Pregnant Women - A Case Control Study. J Clin and Diagn Res. 2013 Aug;7(8):1776-8.
34. Barak S, Oettinger-Barak O, Machtei EE, Sprecher H, Ohel G. Evidence of periopatho-genic microorganisms in placentas of women with preeclampsia. J Periodontol. 2007 Apr;78(4):670-6.
35. Varshney S, Gautam A. Poor periodontal health as a risk factor for development of pre-eclampsia in pregnant women. J Indian Soc Periodontol. 2014 May;18(3):321-5.
36. Kunnen A, van Doormaal JJ, Abbas F, Aarnoudse JG, van Pampus MG, Faas MM. Periodontal disease and pre-eclampsia: a systematic review. J Clin Periodontol. 2010 Dec; 37(12):1075-87.
37. Taghzouti N, Xiong X, Gornitsky M, Chandad F, Voyer R, Gagnon G, et al. Periodontal dis-ease is not associated with preeclampsia in Ca-nadian pregnant women. J Periodontol. 2012 Jul; 83(7): 871-7.
38. Zi MY, Longo PL, Bueno-Silva B, Mayer MP. Mechanisms involved in the association be-tween periodontitis and complications in preg-nancy. Front Public Health. 2015 Jan 29;2:290.
39. Scannapieco FA, Bush RB, Paju S. Periodontal disease as a risk factor for adverse pregnancy outcomes. A systematic review. Ann Periodon-tol. 2003 Dec;8(1):70-8.
40. Herrera JA, Parra B, Herrera E, Botero JE, Arce RM, Contreras A, et al. Periodontal disease se-verity is related to high levels of C-reactive protein in pre-eclampsia. J Hypertens. 2007 Jul; 25 (7):1459-64.
41. Kunnen A, Blaauw J, van Doormaal JJ, van Pampus MG, van der Schans CP, Aarnoudse JG, et al. Women with a recent history of early-onset pre-eclampsia have a worse periodontal condi-tion. J Clin Periodontol. 2007 Mar;34(3):202-7.
42. Vivares-Builes AM, Rangel-Rincón LJ, Botero JE, Agudelo-Suárez AA. Gaps in knowledge about the association between maternal perio-dontitis and adverse obstetric outcomes: an um-brella review. J Evid Based Dent Pract. 2018 Mar;18(1):1-27.
43. Cota LO, Guimarães AN, Costa JE, Lorentz TC, Costa FO. Association between maternal periodontitis and an increased risk of preeclampsia. J Periodontol. 2006 Dec;77(12):2063-9.
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Shariatmadar Ahmadi R, Lor A, Sayar F, Kashanian M, Hajisadeghi S. Evaluation of the Association Between Maternal Periodontal Health and Preeclampsia. J Iran Dent Assoc 2018; 30 (2) :58-65
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Volume 30, Issue 2 (4-2018) Back to browse issues page
Journal of Iranian Dental Association

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