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:: Volume 16, Issue 3 (Foll Text in Persian 2004) ::
J Iran Dent Assoc 2004, 16(3): 64-68 Back to browse issues page
‌Differential diagnosis of myoxid lesions in head and neck area ‌‌with special staining of mucin
Mohammad Eslami * , Mehdi Ashoori
Abstract:   (14547 Views)

‌Differential diagnosis of myoxid lesions in head and neck area ‌‌with special staining of mucin

 Dr. M. Eslami* - Dr. M. Ashoori**

 *- Associate Professor of Oral pathology Dept. - Faculty of Dentistry - Tehran University of Medical Sciences.

** - Assistant Professor of Oral pathology Dept. - Faculty of Dentistry - Kerman University of Medical Sciences.

Background and aim: Myxoid histological pattern is of nonspecific features that is seen in most of benign and malignant lesions occupying a great mass of them. Thus, histopathologic diagnosis depends on a careful and precise investigation. The aim of this study was to differentiate between mucins in myxoid tissues through histochemical staining.

Materials and Methods: Archives of three important educational pathology departments (Facutty of Dentistry of Tehran University, cancer institute of Imam Khomeini hospital and Amir alam hospital) were investigated and information on head and neck tumors with myxoid histopathologic pattern were worked out, then slides and paraffin embeded blocks were studied. Tissue slides of 5mm thickness were stained with PAS/Alcian blue technique and studied under light microscope. The notable standard was the predominant stain of mucin in histological field.

Results: The study of 41histologic slides countaining: malignant fibrous histocytoma (MFH)(n=4), Rhabdomyosarwma (n=6),Chondrosar coma (n=6), Schwannoma (n=7), Neurofibroma (n= 8), Pleomorphic adenoma (n=4) and Odontogenic myxoma (n=6), revealed that neurologic derived lesions and Rhabdomyo sarcoma and MFH had notable red field (neutral mucin nature) where as chondrosarcoma, pleomorphic adenoma and odontogenic myxoma had notable blue field (acidic mucin nature).

Conclusion: Despite limited cases, the results showed that different nature of mucins in different lesions can be considered as a good criteria for differential diagnosis, however, more detailed studies are recommended.

Key Words: Myxoid - Histopathologic differentiation - Mucins - Special staining of PAS /Alcian blue.

Keywords: Myxoid, Histopathologic differentiation, Mucins, Special staining of PAS /Alcian blue
     
Type of Study: Research | Subject: General
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Eslami M, Ashoori M. ‌Differential diagnosis of myoxid lesions in head and neck area ‌‌with special staining of mucin. J Iran Dent Assoc 2004; 16 (3) :64-68
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 16, Issue 3 (Foll Text in Persian 2004) Back to browse issues page
Journal of Iranian Dental Association

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This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

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