Journal of Iranian Dental Association
J Iran Dent Assoc
Medical Sciences
http://jida.ir
23
journal23
2383-3041
10.52547/jida
en
jalali
1392
10
1
gregorian
2014
1
1
26
1
online
1
fulltext
en
Comparison of Salivary Cotinine Concentration in Cigarette Smokers, Water Pipe Smokers and Non–Smokers
Oral Medicine
Oral Medicine
Original
Original
<p> <strong> Background and Aim </strong><strong>: </strong>Water pipe smoking has become a public health hazard. The aim of this study was to measure and compare the concentration of salivary cotinine in cigarette smokers, water pipe smokers and nonsmokers .</p>
<p> <strong> Materials and Methods </strong><strong>: </strong>Forty-eight volunteers (16 cigarette smokers, 16 water pipe smokers and 16 nonsmokers) participated in this cross-sectional study. High sensitivity Salivary Cotinine Quantitative enzyme immunoassay kit was used to measure the salivary cotinine concentration. Non-parametric Kruskal Wallis test, Pearson’s correlation coefficient and linear regression were used to determine the correlation between number of cigarettes smoked and concentration of cotinine .</p>
<p> <strong> Results </strong><strong>: </strong>The mean concentration of salivary cotinine was 223.74(±181.56) ng/ml (the highest) in cigarette smokers, 106.24 (±135.23) ng/ml in water pipe smokers and 0.73(±1.24) ng/ml in nonsmokers. The difference in this respect among the 3 groups was statistically significant (P<0.0001). In smokers, the level of salivary cotinine increased by 1.84 ng/ml per each time of cigarette smoking per week. This increase was 14.57 ng/ml per each time of water pipe consumption per week .</p>
<p> <strong> Conclusion </strong><strong>: </strong>The mean concentration of salivary cotinine was significantly higher among cigarette smokers compared to water pipe smokers and nonsmokers. However, one time consumption of water pipe caused a greater rise in salivary cotinine level compared to cigarette smoking .</p>
<p></p>
Cotinine , Saliva , Smoking , Tobacco
39
45
http://jida.ir/browse.php?a_code=A-10-1-744&slc_lang=en&sid=1
Maryam
Rabiei
rabiei@gums.ac.ir
2300319475328460019822
2300319475328460019822
Yes
Associate Professor, Department of Oral and Maxillofacial Medicine, School of Dentistry, Guilan University of Medical Sciences. Guilan, Iran
Morteza
Rahbar Taramsar
2300319475328460019823
2300319475328460019823
No
Assistant Professor, Department of Legal Medicine and Toxicology, School of Medicine, Guilan University of Medical Sciences. Guilan, Iran
Mehrdad
Sadegh Kanjani
2300319475328460019824
2300319475328460019824
No
PHD Reference laboratory, Guilan University of Medical Sciences. Guilan, Iran
Ehsan
Kazemnezhad Leyli
2300319475328460019825
2300319475328460019825
No
Assistant Professor, Department of Biostatistics, School of Medicine, Guilan University of Medical Sciences. Guilan, Iran
Hosain
Masoudi Rad
2300319475328460019826
2300319475328460019826
No
Assistant Professor, Department of Endodontics, School of Dentistry, Guilan University of Medical Sciences. Guilan, Iran
Mohammad
Jafari Farshami
2300319475328460019827
2300319475328460019827
No
Dentist