Journal of Iranian Dental Association
J Iran Dent Assoc
Medical Sciences
http://jida.ir
23
journal23
2383-3041
10.52547/jida
en
jalali
1397
10
1
gregorian
2019
1
1
31
1
online
1
fulltext
en
Oral Lichen Planus or Oral Lichenoid Reaction?
A Literature Review
Oral Medicine
Oral Medicine
Review
<strong>Background and Aim: </strong>Oral lichen planus (OLP) is a chronic, inflammatory, T-cell-mediated autoimmune oral mucosal disease. Oral lichenoid lesions develop as a type IV hypersensitivity reaction. Both of these entities are potential precancerous conditions; this adds to their clinical significance. The purpose of this literature review was to detect the similarities and the differences of these lesions to enhance the information of colleagues in managing these groups of patients.<br>
<strong>Materials and Methods: </strong>For this review, we searched Cochrane, Medline, and Embase databases from January 1990 to the end of October 2018. A total of 96 published pa-pers, including review papers, case reports, cohort studies, case-control studies, and meta-analysis studies, were included and analyzed.<br>
<strong>Results: </strong>OLP and oral lichenoid reactions are two distinct diseases. They can be clinically similar but they have different etiologic factors. A histopathological study is necessary to differentiate them.<br>
<strong>Conclusion: </strong>The definitive diagnosis of these conditions is extremely important given their potentially premalignant nature. A timely diagnosis probably results in proper management. Based on the present research, the final differentiation between OLP and oral Lichenoid reactions relies on both clinical and histopathological manifestations according to the modified World Health Organization (WHO) criteria.
Oral Lichen Planus, Oral Lichenoid Reactions, Oral Lichenoid Lesions
40
57
http://jida.ir/browse.php?a_code=A-10-1-925&slc_lang=en&sid=1
Farzaneh
Agha-Hosseini
2300319475328460021589
2300319475328460021589
No
Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Oral and Maxillofacial Medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
Mohammad
Samami
m_samami@razi.tums.ac.ir
2300319475328460021590
2300319475328460021590
Yes
Assistant Professor, Oral and Maxillofacial Medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
Fatemeh
Tavakol
2300319475328460021591
2300319475328460021591
No
Assistant Professor, Oral and Maxillofacial Medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
Elahe
Ghasemzadeh Hoseini
2300319475328460021592
2300319475328460021592
No
Assistant Professor, Oral and Maxillofacial Medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran