Iranian Dental Association Journal of Iranian Dental Association 3060-8201 27 1 2015 01 01 Comparative Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Resin Infiltrant on Brown Spot Color Parameters after Using 20% Carbamide Peroxide 43 52 EN Farzaneh Shirani Hale Khalili Marjan Mehravaran Journal Article 2015 04 13 2015 04 13 Background and Aim: Tooth-colored restorations are the current strategy for treatment of aesthetically unpleasant brown spots (BSs). Considering the importance of conserva-tive dentistry, this study aimed to assess the effect of resin infiltrant (RI) and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) after the application of 20% carbamide peroxide (CP) on BS color parameters in the esthetic zone. Materials and Methods: This experimental study was conducted on 70 extracted sound human teeth with BSs. The specimens were first subjected to the application of 20% CP and were then randomly divided into two groups of CPP-ACP and RI. Specimens were subjected to colorimetry before the intervention, after bleaching and after the application of RI or CPP-ACP using a spectrophotometer. Data were statistically analyzed using SPSS version 20, paired t-test, independent t-test and repeated measures ANOVA with P<0.05 level of significance. Results: CP (20%) significantly increased the L* and b* and decreased the a* parameter (p<0.001). CPP-ACP caused no change in a* and b* parameters of BS (p>0.05) howev-er, the L* significantly increased (p<0.001). RI significantly decreased the a* parameter (p<0.001) but the reduction in L* and increase in b* were not significant (p>0.05). Com-parison of the two groups revealed that only the color change (ΔE) during the bleaching procedure was significant (p<0.001). ΔE of BS and the adjacent enamel did not change significantly in any step of the procedure in the two groups (p>0.05). Conclusion: Based on the results, aesthetically unpleasant BSs on teeth may be treated using a bleaching agent along with RI or CPP-ACP. RI seems to have a superior efficacy in increasing the translucency compared to CPP-ACP.