Iranian Dental Association Journal of Iranian Dental Association 3060-8201 30 2 2018 04 01 Oral Focal Mucinosis: A Case Report and Literature Review 82 89 10.30699/JIsdreir.30.2.82 EN Farzaneh Agha-Hosseini Maryam-Sadat Sadrzadeh-Afshar https://orcid.org/https://orcid.org/0000-0001-8277-3805 Journal Article 10.30699/JIsdreir.30.2.82 2018 07 18 2018 07 18 Introduction: Oral focal mucinosis (OFM) is the soft tissue counterpart of cutaneous fo-cal mucinosis (CFM) and is often misdiagnosed as an oral myxoma. OFM occurs during the fourth and fifth decades of life, predominantly in women (two females per male).<br> Case Report: A 22-year-old lactating female presented with a growing painless, sessile tumor with pale pink color and a lobulated surface with ulcers at the depths of interlobular fissures in the premolar-molar area of the left mandibular alveolar ridge, dating back one year. The tumor was completely excised. No recurrence was observed during the follow-ups over the next three years.<br> Conclusion: The current case appears to be the only one with an OFM reported during the breastfeeding period; therefore, the role of hormonal factors in the pathogenesis of the lesion should be taken into consideration.