Iranian Dental Association Journal of Iranian Dental Association 3060-8201 30 3 2018 07 01 Relationship Between Body Mass Index, Lipid Profile and Dental Caries 106 112 10.30699/JIsdreir.30.3.106 EN Fatemeh Ahmadi-Motamayel https://orcid.org/https://orcid.org/0000-0002-7138-7690 Hamidreza Abdolsamadi Mohammad Taghi Goodarzi Zohreh Jamshidi Ali Mahdavinezhad Journal Article 10.30699/JIsdreir.30.3.106 2018 10 08 2018 10 08 Background and Aim: Dental caries is the most common infectious, non-communicable, chronic disease worldwide. Obesity and overweight are major public health problems. Both dental caries and obesity have multi-factorial etiology. The aim of the present study was to determine the possible correlation between the body mass index (BMI), lipid profile and dental caries in two groups of high-school students with active caries (AC) and no caries (CF) in Hamadan, Iran.<br> Materials and Methods: In this case-control study, 118 high-school students between 15-19 years were divided into two groups of AC and CF. All clinical examinations were carried out by a single examiner. Blood samples were obtained from the antecubital vein. Lipid profile was assessed by the enzymatic method using an auto-analyzer. Data were analyzed using Stata.11 software. Statistical comparisons were made using Stu-dent’s t-test and chi-square test.<br> Results: BMI was significantly lower in AC group than CF group (P=0.008). Males had higher BMI than females (P=0.056). CF group had significantly lower level of triglycer-ides (P=0.01), cholesterol (P=0.02) and low-density lipoprotein (LDL) (P=0.02) than AC group.<br> Conclusion: Our results showed that dental caries adversely affects the systemic growth pattern, and students with dental caries had lower BMI than others. Altered lipid profile had a higher frequency in AC group. Dental caries and obesity are both multi-factorial diseases; hence, well-designed epidemiologic studies on the same age group need to be performed in the future taking into account the socioeconomic and cultural factors.<br>