Iranian Dental Association Journal of Iranian Dental Association 3060-8201 33 1-2 2021 01 01 Central Mucoepidermoid Carcinoma with Non-Hodgkin Lymphoma: A Case Report 39 43 10.52547/jida.33.1.2.39 EN Sayed Mohammad Razavi https://orcid.org/0000-0002-3504-9424 Bijan Movahedian Attar Saeedeh Khalesi https://orcid.org/0000-0002-6740-3352 Journal Article 10.52547/jida.33.1.2.39 2021 07 10 2021 01 11 Introduction: Central mucoepidermoid carcinoma (CMEC) is a rare primary intraosseous bony lesion. The mandible is more commonly affected than the maxilla. CMEC is frequently misdiagnosed radiographically and clinically as a benign odontogenic tumor or cyst.<br> Case Presentation: We present a rare case with a secondary malignant neoplasm. A male patient was initially diagnosed with B-cell non-Hodgkin lymphoma. Three months after his initial diagnosis, he presented with a large painless mass in the anterior region of his mandible. Histopathological examination revealed low‐grade CMEC.<br> Conclusion: We reported a very rare case of CMEC in a patient treated for non-Hodgkin lymphoma without radiotherapy. Previous cases of secondary CMEC have demonstrated an increased risk in patients with leukemia/lymphoma after radio-therapy.