[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 28, Issue 1 (1-2016) ::
J Iran Dent Assoc 2016, 28(1): 20-33 Back to browse issues page
A Review of Endodontic Bioceramics
Hadi Assadian1, Ehsan Hamzelouei Moghaddam * 2, Azadeh Amini3, Kumarz Nazari Moghaddam4, Mohadeseh Hashemzehi5
1- Assistant Professor, Department of Endodontics, School of Dentistry, Shahed University, Tehran, Iran
2- Assistant Professor, Department of Endodontics, School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran , hamzelouei@yahoo.com
3- Postgraduate Student, Department of Endodontics, School of Dentistry, Islamic Azad University, Tehran, Iran
4- Associate Professor, Department of Endodontics, School of Dentistry, Shahed University, Tehran, Iran
5- Postgraduate Student, Department of Endodontics, School of Dentistry, Shahed University, Tehran, Iran
Abstract:   (4077 Views)

Background and Aim: The use of ceramics has a long history. A new category of these materials was used in medicine in 1960 introduced as bioceramics. Biocompatibility, osteoinductivity and sealing ability are among the most favorable characteristics of endodontic bioceramics. Introduction of mineral trioxide aggregate (MTA) revolutionized endodontics and this new era is progressively growing.

Materials and Methods: This article reviews endodontic bioceramic materials in the Iranian market such as different types of MTA (ProRoot, Angelus, Root MTA), calcium enriched mixture (CEM) cement, Endo Sequence, iRoot products and MTA Fill apex sealer. Electronic search was carried out for the existing literature in PubMed, Medline and Google Scholar from July 1995 to January 2016 and more clinically applicable data were collected.

Conclusion: Favorable characteristics and promising results of bioceramics make them suitable for use in endodontics and new products of this generation are increasingly introduced to the dental market.

Keywords: Endodontics, Bioceramics, Root Canal Filling Materials, Root Canal sealant
Full-Text [PDF 452 kb]   (5633 Downloads)    
Type of Study: Review | Subject: Endodontics
1. Sukumaran V, Bharadwaj N. Ceramics in dental applications. Trends Biomater. 2006;20(1):7-11.
2. Ceramic. Available at:https://en.wikipedia.org/ wiki/Ceramic/Accessed August 27, 2015.
3. Hench LL. The story of Bioglass®. J Mater Sci Mater Med. 2006 Nov; 17(11):967-78.
4. Malhotra S, Hegde MN, Shetty C. Bioceramic technology in endodontics. Br J Med and Med Res. 2014 Apr; 4(12):2446-2454.
5. Trope M, Bunes A, Debelian G. Root filling materials and techniques: Bioceramics a new hope? Endod Topics. 2015 May;32(1):86-96.
6. Best S, Porter A, Thian E, Huang J. Bioceramics: Past, present and for the future. J of the Europ Ceramic Soc. 2008 Dec;28(7):1319-27.
7. Wang Z. Bioceramic materials in endodontics. Endod Topics. 2015 May;32(1):3-30.
8. Koch K, Brave D. Bioceramic technology-the gamechanger in endodontics. Endod Practice US. 2009; َ Apr:13-7.
9. Candeiro GT, Correia FC, Duarte MA, Ribeiro-Siqueira DC, Gavini G. Evaluation of radiopacity, pH, release of calcium ions, and flow of a bioceramic root canal sealer. J of Endod. 2012 Jun; 38(6):842-5.
10. Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chemical properties of a new root-end filling material. J Endod. 1995 Jul; 21(7):349-53.
11. Primus CM, Gutmann JL, Yapp R, Tay F. Physical Properties of New Generation Tricalcium Silicate Dental Materials. Bioceram Dev Appl. 2014 Oct;4(1):1-9.
12. Shen Y, Peng B, Yang Y, Ma J, Haapasalo M. What do different tests tell about the mechanical and biological properties of bioceramic materials? Endod Topics. 2015 May; 32(1):47-85.
13. Camilleri J. Hydration mechanisms of mineral trioxide aggregate. Int Endod J. 2007 Jun; 40(6):462-70.
14. Dammaschke T, Gerth HU, Züchner H, Schäfer E. Chemical and physical surface and bulk material characterization of white ProRoot MTA and two Portland cements. Dent Mater. 2005 Aug; 21(8):731-8.
15. Asgary S, Parirokh M, Eghbal MJ, Stowe S, Brink F. A qualitative X-ray analysis of white and grey mineral trioxide aggregate using compositional imaging. J Mater Sci Mater Med. 2006 Feb;17(2):187-91.
16. Song JS, Mante FK, Romanow WJ, Kim S. Chemical analysis of powder and set forms of Portland cement, gray ProRoot MTA, white ProRoot MTA, and gray MTA-Angelus. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 2006 Dec;102(6):809-15.
17. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J, Kheirieh S, Brink F. Comparison of mineral trioxide aggregate's composition with Portland cements and a new endodontic cement. J Endod. 2009 Feb; 35(2):243-50.
18. Camilleri J, Montesin FE, Brady K, Sweeney R, Curtis RV, Ford TRP. The constitution of mineral trioxide aggregate. Dent Mater. 2005 Apr; 21(4): 297-303.
19. Holland R, De Souza V, Nery MJ, Otoboni Filho JA, Bernabé PF, Dezan E. Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide. J of Endod. 1999 Mar;25(3):161-6.
20. Holland R, Souza Vd, Nery MJ, Faraco Júnior IM, Bernabé PFE, Otoboni Filho JA, et al. Reaction of rat connective tissue to implanted dentin tubes filled with a white mineral trioxide aggregate. Braz Dent J. 2002;13(1):23-6.
21. Gandolfi MG, Taddei P, Tinti A, Prati C. Apatite‐ forming ability (bioactivity) of ProRoot MTA. Int Endod J. 2010 Oct;43(10):917-29.
22. Chng HK, Islam I, Yap AU, Tong YW, Koh ET. Properties of a new root-end filling material. J Endod. 2005 Sep;31(9):665-8.
23. Storm B, Eichmiller FC, Tordik PA, Goodell GG. Setting expansion of gray and white mineral trioxide aggregate and Portland cement. J Endod. 2008 Jan; 34(1):80-2.
24. Ding SJ, Kao CT, Shie MY, Hung C, Huang TH. The physical and cytological properties of white MTA mixed with Na 2 HPO 4 as an accelerant. J Endod. 2008 Jun;34(6):748-51.
25. Budig CG, Eleazer PD. In vitro comparison of the setting of dry ProRoot MTA by moisture absorbed through the root. J Endod. 2008 Jun; 34(6):712-4.
26. Gancedo-Caravia L, Garcia-Barbero E. Influence of humidity and setting time on the push-out strength of mineral trioxide aggregate obturations. J Endod. 2006 Sep;32(9):894-6.
27. Walker MP, Diliberto A, Lee C. Effect of setting conditions on mineral trioxide aggregate flexural strength. J Endod. 2006 Apr; 32(4): 334-6.
28. Shie MY, Huang TH, Kao CT, Huang CH, Ding SJ. The effect of a physiologic solution pH on properties of white mineral trioxide aggregate. J Endod. 2009 Jan;35(1):98-101.
29. Fridland M, Rosado R. MTA solubility: a long term study. J Endod. 2005 May; 31(5):376-9.
30. Hsieh SC, Teng NC, Lin YC, Lee PY, Ji DY, Chen CC, et al. A novel accelerator for improving the handling properties of dental filling materials. J Endod. 2009 Sep; 35(9):1292-5.
31. Komabayashi T, Spångberg LS. Comparative analysis of the particle size and shape of commercially available mineral trioxide aggregates and Portland cement: a study with a flow particle image analyzer. J Endod. 2008 Jan; 34(1):94-8.
32. Kogan P, He J, Glickman GN, Watanabe I. The effects of various additives on setting properties of MTA. J Endod. 2006 Jun; 32(6):569-72.
33. Huang TH, Shie MY, Kao CT, Ding SJ. The effect of setting accelerator on properties of mineral trioxide aggregate. J Endod. 2008 May; 34(5):590-3.
34. Wiltbank KB, Schwartz SA, Schindler WG. Effect of selected accelerants on the physical properties of mineral trioxide aggregate and Portland cement. J Endod. 2007 Oct; 33(10):1235-8.
35. Ber BS, Hatton JF, Stewart GP. Chemical modification of ProRoot MTA to improve handling characteristics and decrease setting time. J Endod. 2007 Oct;33(10):1231-4.
36. Zapf AM, Chedella SC, Berzins DW. Effect of additives on mineral trioxide aggregate setting reaction product formation. J Endod. 2015 Jan; 41 (1):88-91.
37. Jafarnia B, Jiang J, He J, Wang Y-H, Safavi KE, Zhu Q. Evaluation of cytotoxicity of MTA employing various additives. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 2009 May; 107(5):739-44.
38. Lee YL, Lee BS, Lin FH, Lin AY, Lan WH, Lin CP. Effects of physiological environments on the hydration behavior of mineral trioxide aggregate. Biomaterials. 2004 Feb; 25(5):787-93.
39. Shokouhinejad N, Nekoofar MH, Iravani A, Kharrazifard MJ, Dummer PM. Effect of acidic environment on the push-out bond strength of mineral trioxide aggregate. J Endod. 2010 May; 36 (5):871-4.
40. Namazikhah MS, Nekoofar MH, Sheykhrezae MS, Salariyeh S, Hayes SJ, Bryant ST, et al. The effect of pH on surface hardness and microstructure of mineral trioxide aggregate. Int Endod J. 2008 Feb; 41(2):108-16.
41. Kayahan MB, Nekoofar MH, Kazandağ M, Canpolat C, Malkondu O, Kaptan F, et al. Effect of acid‐etching procedure on selected physical properties of mineral trioxide aggregate. Int Endod J. 2009 Nov; 42(11):1004-14.
42. Belobrov I, Parashos P. Treatment of tooth discoloration after the use of white mineral trioxide aggregate. J Endod. 2011 Jul; 37(7):1017-20.
43. Bortoluzzi EA, Araújo GS, Tanomaru JMG, Tanomaru-Filho M. Marginal gingiva discoloration by gray MTA: a case report. J Endod. 2007 Mar; 33(3):325-7.
44. Felman D, Parashos P. Coronal tooth discoloration and white mineral trioxide aggregate. J Endod. 2013 Apr;39(4):484-7.
45. Han L, Okiji T. Bioactivity evaluation of three calcium silicate‐based endodontic materials. Int Endod J. 2013 Sep;46(9):808-14.
46. Ioannidis K, Mistakidis I, Beltes P, Karagiannis V. Spectrophotometric analysis of coronal discolouration induced by grey and white MTA. Int Endod J. 2013 Feb;46(2):137-44.
47. Akbari M, Rouhani A, Samiee S, Jafarzadeh H. Effect of dentin bonding agent on the prevention of tooth discoloration produced by mineral trioxide aggregate. Int J Dent. 2012;2012:563203.
48. Camilleri J. Color stability of white mineral trioxide aggregate in contact with hypochlorite solution. J Endod. 2014 Mar;40(3):436-40.
49. Tsujimoto M, Ookubo A, Wada Y, Matsunaga T, Tsujimoto Y, Hayashi Y. Surface changes of mineral trioxide aggregate after the application of bleaching agents: electron microscopy and an energy-dispersive X-ray microanalysis. J Endod. 2011 Feb;37(2):231-4.
50. Shahi S, Rahimi S, Lotfi M, Yavari H, Gaderian A. A comparative study of the biocompatibility of three root-end filling materials in rat connective tissue. J Endod. 2006 Aug; 32 (8):776-80.
51. Yaltirik M, Ozbas H, Bilgic B, Issever H. Reactions of connective tissue to mineral trioxide aggregate and amalgam. J Endod. 2004 Feb; 30 (2):95-9.
52. Lotfi M, Vosoughhosseini S, Saghiri MA, Mesgariabbasi M, Ranjkesh B. Effect of white mineral trioxide aggregate mixed with disodium hydrogen phosphate on inflammatory cells. J Endod. 2009 May;35(5):703-5.
53. Gomes-Filho JE, de Faria MD, Bernabé PF, Nery MJ, Otoboni-Filho JA, Dezan-Júnior E, et al. Mineral trioxide aggregate but not light-cure mineral trioxide aggregate stimulated mineralization. J Endod. 2008 Jan;34(1):62-5.
54. Oliveira MG, Xavier CB, Demarco FF, Pinheiro AL, Costa AT, Pozza DH. Comparative chemical study of MTA and Portland cements. Braz Dent J. 2007;18(1):3-7.
55. Duarte MA, Demarchi AC, Yamashita JC, Kuga MC, Fraga Sde C. pH and calcium ion release of 2 root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 2003 Mar; 95(3):345-7.
56. de Vasconcelos BC, Bernardes RA, Cruz SM, Duarte MA, Padilha Pde M, Bernardineli N, et al. Evaluation of pH and calcium ion release of new root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 2009 Jul; 108(1): 135-9.
57. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review-part I: chemical, physical, and antibacterial properties. J Endod. 2010 Jan;36(1):16-27.
58. Froughreyhani M, Milani A, Barakatein B, Shiezadeh V. Treatment of strip perforation using Root MTA: A case report. Iran Endod J. 2013 Spring; 8(2):80-83.
59. Moazami F, Shahsiah S. The cellular behavior and SEM evaluation of ProRoot and Root MTAs on fibroblast L929. Iran Endod J. 2006 Fall; 1(3): 87-92.
60. Kazem M, Eghbal MJ, Asgary S. Comparison of bacterial and dye microleakage of different root-end filling materials. Iran Endod J. 2010 Winter; 5 (1):17-22.
61. Salles LP, Gomes-Cornélio AL, Guimaraes FC, Herrera BS, Bao SN, Rossa-Junior C, et al. Mineral trioxide aggregate–based endodontic sealer stimulates hydroxyapatite nucleation in human osteoblast-like cell culture. J Endod. 2012 Jul;38(7):971-6.
62. Oloomi K, Saberi E, Mokhtari H, Mokhtari Zonouzi HR, Nosrat A, Nekoofar MH, et al. Evaluation of the effect of blood contamination on the compressive strength of MTA modified with hydration accelerators. Restor Dent Endod. 2013 Aug; 38(3):128-33.
63. Jahromi Z, Razavi S.M, Esfahanian V, Feizi GH. Histological evaluation of inflammation after sealing furcating perforation in dog's teeth by four materials. Dent Res J. 2006 Autumn-Winter; 3(2): 1-10.
64. Sheykhrezai MS, Aligholi M, Ghorbanzadeh R, Bahador A. A comparative study of antimicrobial activity of ProRoot MTA, Root MTA, and Portland cement on Actinobacillus actinomycetemcomitans. Iran Endod J. 2008 Fall; 3(4):129-133.
65. Sharifian MR, Ghobadi M, Shokouhinejad N, Assadian H. Cytotoxicity evaluation of ProRoot MTA, Root MTA and Portland cement on human gingival fibroblasts. Iran Endod J. 2007 Fall; 2(3): 91-94.
66. Camilleri J, Kralj P, Veber M, Sinagra E. Characterization and analyses of acid‐extractable and leached trace elements in dental cements. Int Endod J. 2012 Aug;45(8):737-43.
67. Setbon HM, Devaux J, Iserentant A, Leloup G, Leprince JG. Influence of composition on setting kinetics of new injectable and/or fast setting tricalcium silicate cements. Dent Mater. 2014 Dec; 30(12):1291-303.
68. Keskin C, Demiryurek EO, Ozyurek T. Color Stabilities of Calcium Silicate–based Materials in Contact with Different Irrigation Solutions. J Endod. 2015 Mar;41(3):409-11.
69. Grech L, Mallia B, Camilleri J. Characterization of set Intermediate Restorative Material, Biodentine, Bioaggregate and a prototype calcium silicate cement for use as root‐end filling materials. Int Endod J. 2013 Jul; 46(7):632-41.
70. Han L, Okiji T. Uptake of calcium and silicon released from calcium silicate–based endodontic materials into root canal dentine. Int Endod J. 2011 Dec;44(12):1081-7.
71. Atmeh AR, Chong EZ, Richard G, Festy F, Wat-son TF. Dentin-cement Interfacial Interaction Calcium Silicates and Polyalkenoates. J Dent Res. 2012 May; 91(5):454-9.
72. Guneser MB, Akbulut MB, Eldeniz AU. Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials. J Endod. 2013 Mar; 39(3):380-4.
73. Leiendecker AP, Qi YP, Sawyer AN, Niu LN, Agee KA, Loushine RJ, et al. Effects of Calcium Silicate–based Materials on Collagen Matrix Integrity of Mineralized Dentin. J Endod. 2012 Jun; 38(6):829-33.
74. Marconyak LJ Jr, Kirkpatrick TC, Roberts HW, Roberts MD, Aparicio A, Himel VT, et al. A Comparison of Coronal Tooth Discoloration Elicited by Various Endodontic Reparative Materials. J Endod. 2016 Mar;42(3):470-3.
75. Shokouhinejad N, Nekoofar MH, Pirmoazen S, Shamshiri AR, Dummer PM. Evaluation and Comparison of Occurrence of Tooth Discoloration after the Application of Various Calcium Silicate-based Cements: An Ex Vivo Study. J Endod. 2016 Jan; 42(1):140-4.
76. Nowicka A, Lipski M, Parafiniuk M, Sporniak-Tutak K, Lichota D, Kosierkiewicz A, et al. Response of human dental pulp capped with biodentine and mineral trioxide aggregate. J Endod. 2013 Jun; 39(6):743-7.
77. Bani M, Sungurtekin-Ekçi E, Odabaş ME. Efficacy of Biodentine as an Apical Plug in Nonvital Permanent Teeth with Open Apices: An In Vitro Study. Biomed Res Int. 2015; 2015: 359275. doi: 10.1155/2015/359275. Epub 2015 Sep; 7.
78. Tanalp J, Karapınar-Kazandağ M, Dölekoğlu S, Kayahan MB. Comparison of the radiopacities of different root-end filling and repair materials. ScientificWorldJournal. 2013 Oct;2013:594950.
79. Caron G, Azérad J, Faure MO, Machtou P, Boucher Y. Use of a new retrograde filling material (Biodentine) for endodontic surgery: two case reports. Int J Oral Sci. 2014 Dec; 6(4):250-3.
80. Asgary S, Shahabi S, Jafarzadeh T, Amini S, Kheirieh S. The properties of a new endodontic material. J Endod. 2008 Aug;34(8):990-3.
81. Amini Ghazvini S, Abdo Tabrizi M, Kobarfard F, Akbarzadeh Baghban A, Asgary S.. Ion release and pH of a new endodontic cement, MTA and Portland cement. Iran Endod J. 2009 Spring; 4(2): 74-78.
82. Torabzadeh H, Aslanzadeh S, Asgary S. Radiopacity of Various Dental Biomaterials. Research J of Biological Sci. 2012;7(4):152-8.
83. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J. Effect of two storage solutions on surface topography of two root‐end fillings. Aust Endod J. 2009 Dec; 35(3):147-52.
84. Asgary S, Kamrani F, Taheri S. Evaluation of antimicrobial effect of MTA, calcium hydroxide, and CEM cement. Iran Endod J. 2007 Fall; 2(3): 105-109.
85. Kangarlou A, Sofiabadi S, Yadegari Z, Asgary S. Antifungal effect of calcium enriched mixture cement against Candida albicans. Iran Endod J. 2009 Summer; 4(3):101-105.
86. Asgary S, Eghbal MJ, Parirokh M, Torabzadeh H. Sealing ability of three commercial mineral trioxide aggregates and an experimental root-end filling material. Iran Endod J. 2006 Fall; 1(3):101- 105.
87. Asgary S, Eghbal MJ, Parirokh M. Sealing ability of a novel endodontic cement as a root‐end filling material. J Biomed Mater Res A. 2008 Dec 1;87(3):706-9.
88. Hasheminia M, Nejad SL, Asgary S. Sealing ability of MTA and CEM cement as root-end fillings of human teeth in dry, saliva or blood-contaminated conditions. Iran Endod J. 2010 Autumn; 5(4):151-156.
89. Nosrat A, Seifi A, Asgary S. Pulpotomy in caries‐exposed immature permanent molars using calcium‐enriched mixture cement or mineral trioxide aggregate: a randomized clinical trial. Int J Paediatr Dent. 2013 Jan; 23(1):56-63.
90. Asgary S, Eghbal MJ. The effect of pulpotomy using a calcium-enriched mixture cement versus one-visit root canal therapy on postoperative pain relief in irreversible pulpitis: a randomized clinical trial. Odontology. 2010 Jul;98(2):126-33.
91. Ghajari MF, Jeddi TA, Iri S, Asgary S. Direct pulp-capping with calcium enriched mixture in primary molar teeth: a randomized clinical trial. Iran Endod J. 2010 Winter; 5(1):27-30.
92. Asgary S. Furcal perforation repair using calcium enriched mixture cement. J Conserv Dent. 2010 Jul-Sep; 13(3):156-158.
93. Asgary S, Nosrat A, Seifi A. Management of inflammatory external root resorption by using calcium-enriched mixture cement: a case report. J Endod. 2011 Mar;37(3):411-3.
94. Asgary S, Eghbal MJ, Ehsani S. Periradicular regeneration after endodontic surgery with calcium-enriched mixture cement in dogs. J Endod. 2010 May;36(5):837-41.
95. Nosrat A, Seifi A, Asgary S. Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. J Endod. 2011 Apr; 37(4):562-7.
96. Asgary S, Eghbal MJ. Treatment outcomes of pulpotomy in permanent molars with irreversible pulpitis using biomaterials: a multi-center randomized controlled trial. Acta Odontol Scand. 2013 Jan;71(1):130-6.
97. Asgary S, Eghbal MJ, Ghoddusi J, Yazdani S. One-year results of vital pulp therapy in permanent molars with irreversible pulpitis: an ongoing multicenter, randomized, non-inferiority clinical trial. Clin Oral Investig. 2013 Mar;17(2):431-9.
98. Damas BA, Wheater MA, Bringas JS, Hoen MM. Cytotoxicity comparison of mineral trioxide aggregates and EndoSequence bioceramic root repair materials. J Endod. 2011 Mar;37(3):372-5.
99. Shokouhinejad N, Nekoofar MH, Razmi H, Sajadi S, Davies TE, Saghiri M, et al. Bioactivity of EndoSequence root repair material and bioaggregate. Int Endod J. 2012 Dec; 45(12):1127-34.
100. Hansen SW, Marshall JG, Sedgley CM. Comparison of intracanal EndoSequence Root Repair Material and ProRoot MTA to induce pH changes in simulated root resorption defects over 4 weeks in matched pairs of human teeth. J Endod. 2011 Apr; 37(4):502-6.
101. Lovato KF, Sedgley CM. Antibacterial activity of endosequence root repair material and proroot MTA against clinical isolates of Enterococcus faecalis. J of Endod. 2011 Nov; 37 (11):1542-6.
102. Wang Z, Ma J, Shen Y, Haapasalo M. Acidic pH weakens the microhardness and microstructure of three tricalcium silicate materials. Int Endod J. 2015 Apr; 48(4):323-32.
103. Modareszadeh MR, Di Fiore PM, Tipton DA, Salamat N. Cytotoxicity and alkaline phosphatase activity evaluation of endosequence root repair material. J Endod. 2012 Aug; 38(8):1101-5.
104. Machado J, Johnson JD, Paranjpe A. The Effects of Endosequence Root Repair Material on Differentiation of Dental Pulp Cells. J Endod. 2016 Jan; 42(1):101-105.
105. Chen I, Karabucak B, Wang C, Wang HG, Koyama E, Kohli MR, et al. Healing after Root-end Microsurgery by Using Mineral Trioxide Aggregate and a New Calcium Silicate–based Bioceramic Material as Root-end Filling Materials in Dogs. J Endod. 2015 Mar; 41(3):389-99.
106. Khalil WA, Abunasef SK. Can Mineral Trioxide Aggregate and Nanoparticulate EndoSequence Root Repair Material Produce Injurious Effects to Rat Subcutaneous Tissues? J Endod. 2015 Jul;41(7):1151-1156.
107. Beatty H, Svec T. Quantifying Coronal Tooth Discoloration Caused by Biodentine and EndoSequence Root Repair Material. J Endod. 2015 Dec; 41(12):2036-9.
108. Jiang Y, Zheng Q, Zhou X, Gao Y, Huang D. A comparative study on root canal repair materials: a cytocompatibility assessment in L929 and MG63 cells. ScientificWorldJournal. 2014 Jan; 2014: 463826.
109. Shi S, Bao ZF, Liu Y, Zhang DD, Chen X, Jiang LM, et al. Comparison of in vivo dental pulp responses to capping with iRoot BP Plus and mineral trioxide aggregate. Int Endod J. 2016 Feb; 49(2):154-160.
110. De‐Deus G, Canabarro A, Alves GG, Marins JR, Linhares AB, Granjeiro J. Cytocompatibility of the ready‐to‐use bioceramic putty repair cement iRoot BP Plus with primary human osteoblasts. Int Endod J. 2012 Jun;45(6):508-13.
111. Hess D, Solomon E, Spears R, He J. Retreatability of a bioceramic root canal sealing material. J Endod. 2011 Nov;37(11):1547-9.
112. Zhang W, Li Z, Peng B. Assessment of a new root canal sealer's apical sealing ability. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 2009 Jun; 107(6):e79-e82.
113. Nagas E, Uyanik MO, Eymirli A, Cehreli ZC, Vallittu PK, Lassila LV, et al. Dentin moisture conditions affect the adhesion of root canal sealers. J of Endod. 2012 Feb;38(2):240-4.
114. Shokouhinejad N, Gorjestani H, Nasseh AA, Hoseini A, Mohammadi M, Shamshiri AR. Push‐out bond strength of gutta‐percha with a new bioceramic sealer in the presence or absence of smear layer. Aust Endod J. 2013 Dec; 39(3):102-6.
115. Ersahan S, Aydin C. Dislocation resistance of iRoot SP, a calcium silicate–based sealer, from radicular dentine. J Endod. 2010 Dec; 36(12): 2000-2.
116. Amin SA, Seyam RS, El-Samman MA. The effect of prior calcium hydroxide intracanal placement on the bond strength of two calcium silicate–based and an epoxy resin–based endodontic sealer. J Endod. 2012 May; 38(5):696-9.
117. Shokouhinejad N, Hoseini A, Gorjestani H, Raoof M, Assadian H, Shamshiri AR. Effect of phosphate-buffered saline on push-out bond strength of a new bioceramic sealer to root canal dentin. Dent Res J (Isfahan). 2012 Sept; 9(5):595-599.
118. Zhang H, Shen Y, Ruse ND, Haapasalo M. Antibacterial activity of endodontic sealers by modified direct contact test against Enterococcus faecalis. J Endod. 2009 Jul;35(7):1051-5.
119. Loushine BA, Bryan TE, Looney SW, Gillen BM, Loushine RJ, Weller RN, et al. Setting properties and cytotoxicity evaluation of a premixed bioceramic root canal sealer. J Endod. 2011 May;37(5):673-7.
120. Borges RP, Sousa-Neto MD, Versiani MA, Rached-Júnior FA, De-Deus G, Miranda CE, et al. Changes in the surface of four calcium silicate‐containing endodontic materials and an epoxy resin‐based sealer after a solubility test. Int Endod J. 2012 May; 45(5):419-28.
121. Ersahan S, Aydin C. Solubility and apical sealing characteristics of a new calcium silicate-based root canal sealer in comparison to calcium hydroxide-, methacrylate resin-and epoxy resin-based sealers. Acta Odontol Scand. 2013 May-Jul; 71(3-4):857-62.
122. Zhang W, Li Z, Peng B. Effects of iRoot SP on mineralization-related genes expression in MG63 cells. J Endod. 2010 Dec;36(12):1978-82.
123. Zhang W, Peng B. Tissue reactions after subcutaneous and intraosseous implantation of iRoot SP, MTA and AH Plus. Dent Mater J. 2015; 34(6):774-80.
124. Silva EJ, Rosa TP, Herrera DR, Jacinto RC, Gomes BP, Zaia AA. Evaluation of cytotoxicity and physicochemical properties of calcium silicate-based endodontic sealer MTA Fillapex. J Endod. 2013 Feb; 39(2):274-7.
125. Bin CV, Valera MC, Camargo SE, Rabelo SB, Silva GO, Balducci I, et al. Cytotoxicity and genotoxicity of root canal sealers based on mineral trioxide aggregate. J Endod. 2012 Apr; 38(4):495-500.
126. Faria‐Júnior NB, Tanomaru‐Filho M, Berbert FL, Guerreiro‐Tanomaru JM. Antibiofilm activity, pH and solubility of endodontic sealers. Int Endod J. 2013 Aug;46(8):755-62.
127. Morgental RD, Vier‐Pelisser FV, Oliveira SD, Antunes FC, Cogo DM, Kopper P. Antibacterial activity of two MTA‐based root canal sealers. Int Endod J. 2011 Dec; 44(12):1128-33.
128. Sagsen B, Ustün Y, Demirbuga S, Pala K. Push‐out bond strength of two new calcium silicate‐based endodontic sealers to root canal dentine. Int Endod J. 2011 Dec; 44(12):1088-91.
129. Bidar M, Sadeghalhoseini N, Forghani M, Attaran N. Effect of the smear layer on apical seals produced by two calcium silicate-based endodontic sealers. J Oral Sci. 2014 Sept; 56(3):215-9.
130. Sağsen B, Ustün Y, Pala K, Demırbuğa S. Resistance to fracture of roots filled with different sealers. Dent Mater J. 2012;31(4):528-32.
131. Borges ÁH, Orçati Dorileo MC, Dalla Villa R, Borba AM, Semenoff TA, Guedes OA, et al. Physicochemical properties and surfaces morphologies evaluation of MTA FillApex and AH Plus. ScientificWorldJournal. 2014; 2014: 589732.
132. Nikhil V, Bansal P, Sawani S. Effect of technique of sealer agitation on percentage and depth of MTA Fillapex sealer penetration: A comparative in-vitro study. J Conserv Dent: 2015 Mar-Apr; 18(2):119-123.
133. Kok D, Rosa RA, Barreto MS, Busanello FH, Santini MF, Pereira JR, et al. Penetrability of AH plus and MTA fillapex after endodontic treatment and retreatment: A confocal laser scanning microscopy study. Microsc Res Tech. 2014 Jun; 77 (6):467-71.
134. Bósio CC, Felippe GS, Bortoluzzi EA, Felippe MC, Felippe WT, Rivero ER. Subcutaneous connective tissue reactions to iRoot SP, mineral trioxide aggregate (MTA) Fillapex, DiaRoot BioAggregate and MTA. Int Endod J. 2014 Jul; 47 (7):667-74.
135. Zhou HM, Du TF, Shen Y, Wang ZJ, Zheng YF, Haapasalo M. In Vitro Cytotoxicity of Calcium Silicate–containing Endodontic Sealers. J Endod. 2015 Jan;41(1):56-61.
136. Assmann E, Böttcher DE, Hoppe CB, Grecca FS, Kopper PM. Evaluation of bone tissue response to a sealer containing mineral trioxide aggregate. J Endod. 2015 Jan; 41(1):62-6.
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Assadian H, Hamzelouei Moghaddam E, Amini A, Nazari Moghaddam K, Hashemzehi M. A Review of Endodontic Bioceramics. J Iran Dent Assoc 2016; 28 (1) :20-33
URL: http://jida.ir/article-1-1839-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 28, Issue 1 (1-2016) Back to browse issues page
Journal of Iranian Dental Association


This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4570