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:: Volume 27, Issue 1 (1-2015) ::
J Iran Dent Assoc 2015, 27(1): 31-37 Back to browse issues page
Reliability of Fine Needle Aspiration Cytology for Salivary Gland Lesions
Gita Rezvani1 , Farzad Yazdani Bioki2 , Roya Khatami * 3, Hamed Keramat4 , Ali Moadabi4
1- Assistant Professor, Department of Pathology, School of Dentistry, Shahed University. Tehran, Iran
2- Assistant Professor, Department of Pathology, School of Dentistry, Tehran University of Medical Sciences. Tehran, Iran
3- Postgraduate Student, Department of Oral and Dental Diseases, School of Dentistry, Shahed University. Tehran, Iran , Royakhatami74@yahoo.com
4- Postgraduate Student, Department of Oral and Dental Diseases, School of Dentistry, Shahed University. Tehran, Iran
Abstract:   (9465 Views)

Background and Aim: Fine needle aspiration (FNA) cytology is a safe, reliable, mini-mally invasive and cost-effective technique for the diagnosis of salivary gland lesions. This study aimed to assess the accuracy, reliability and diagnostic value of FNA cytology in Iran.

Materials and Methods: A total of 200 records of patients with a history of biopsy or surgical excision of salivary gland lesions along with their histological and cytological examination results were retrieved and evaluated in the Pathology Department of Amir Alam Hospital during 2007-2013. The results of cytological diagnosis were divided into 4 groups of unfavorable, benign, suspicious and malignant. The cytological results were compared with the histological data. The accuracy, sensitivity, specificity, positive predic-tive value (PPV) and negative predictive value (NPV) of FNA cytology were calculated using SPSS version 16.00.

Results: Of the specimens chosen for the study, 173 were from the parotid, 22 from the submandibular and 5 from the minor salivary glands. FNA cytological diagnosis was be-nign in 161 cases, suspicious for malignancy in 4 cases, and malignancy in 35 cases. Of 161 cases diagnosed as benign by FNA cytology, 25 were malignant and the frequency of false positive results was 15.5%. The accuracy, sensitivity, specificity, PPV and NPV of the FNA test were 82, 53, 93, 72 and 84%, respectively.

Conclusion: A good agreement exists between the FNA results and final histopathological diagnosis of salivary gland tumors. Also, this study showed that FNA cytology has mod-erate accuracy and relative diagnostic value for diagnosis of salivary gland lesions.
Keywords: Salivary gland, Fine needle aspiration biopsy, Sensitivity, Specificity, Diagnostic accuracy
Full-Text [PDF 171 kb]   (1851 Downloads)    
Type of Study: Original | Subject: Pathology
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Rezvani G, Yazdani Bioki F, Khatami R, Keramat H, Moadabi A. Reliability of Fine Needle Aspiration Cytology for Salivary Gland Lesions. J Iran Dent Assoc 2015; 27 (1) :31-37
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Volume 27, Issue 1 (1-2015) Back to browse issues page
Journal of Iranian Dental Association

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