[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 27, Issue 4 (10-2015) ::
J Iran Dent Assoc 2015, 27(4): 198-202 Back to browse issues page
Histomorphometric Study of Tissue Reaction to Mini-screws with Composite Coating Implanted in the Maxilla of Rabbits
Mehdi Araghbidi Kashani1, Nooshin Jalayer Naderi *2, Saeid Barande3
1- Assistant Professor, Department of Orthodontics, School of Dentistry, Shahed University, Tehran, Iran
2- Associate Professor, Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahed University, Tehran, Iran , jalayer@shahed.ac.ir
3- Orthodontist, Private Office, Tehran, Iran
Abstract:   (2631 Views)

Background and Aim: Stability of mini-screws in bone depends on mechanical factors in the primary phase and biological factors after osseointegration. mini-screws can transfer thermal shocks in the oral cavity to bone marrow. It has been shown that impaired osseointegration and inflammation can lead to failure of mini-screws. The aim of this study was to compare the tissue response to implanted mini screws with and without composite coating of the head.

Materials and Methods: In this animal study, mini-screws with 1.4mm diameter and 6mm length were implanted in the maxilla of 12 male rabbits. One mini-screw was implanted in each of the right and left quadrants of the maxilla. The right side mini-screws received composite coating on their head. The left side mini screws did not receive coating. In the next three months, cold (1°C) and warm (40°C) water were injected into their mouth 10 times daily. After three months, the rabbits were sacrificed, and paraffinized tissue blocks were prepared. The tissue reaction was examined under light microscopy. The paired t-test and Wilcoxon signed rank test were used for statistical analysis.

Results: The mean rate of osseointegration of mini-screws with and without composite coatings was 32.1±5.3 and 20.4±3.43, respectively. The rate of osseointegration was significantly higher around mini-screws with composite coating than mini-screws without coating (P<0.001). In both groups, the newly formed bone was woven and no inflammatory reaction was noted.

Conclusion: The rate of osseointegration of mini-screws with composite coatingof the head was higher than that of mini-screws without it.

Keywords: Bone Screws, Osseointegration, Thermal Conductivity
Full-Text [PDF 592 kb]   (1099 Downloads)    
Type of Study: Original | Subject: Pathology
1. Vande Vannet B, Sabzevar MM, Wehrbein H, Asscherickx K. Osseointegration of mini screws: A histomorphometric evaluation. Eur J Orthod. 2007 Oct; 29(5):437-42.
2. Kuroda S, Sugawara Y, Deguchi T, Kyung HM, Takano-Yamamoto T. Clinical use of mini screw implants as orthodontic anchorage: success rates and postoperative discomfort. Am J Orthod Dentofacial Orthop. 2007 Jan; 131(1):9-15.
3. Wu J, Bai YX, Wang BK. Biomechanical and histomorphometric characterizations of osseointegration during mini-screw healing in rabbit tibiae. Angle Orthod. 2009 May;79(3):558-63.
4. Handa A, Hedge N, Reddy VP, Chandrashekhar B S, Arun A V, MahendraS. Effect of the thread pitch of orthodontic mini -implant on bone stress- A 3D finite element analysis. E-J Dent. 2011 Oct-Dec; 1(4):91-96.
5. Melsen B, Lang NP. Biological reactions of alveolar bone to orthodontic loading of oral implants. Clin Oral Implants Res. 2001 Apr; 12 (2):144-52.
6. Haanaes HR, Stenvik A, Beyer-Olsen ES, Tryti T, Faehn O. The efficacy of two-stage titanium implants as orthodontic anchorage in the preprosthodontic correction of third molars in adults-a report of three cases. Eur J Orthod. 1991 Aug;13(4):287-92.
7. Guglielmotti MB, Renou S, Cabrini RL. A histomorphometric study of tissue interface by laminar implant test in rats. Int J Oral Maxillo-fac Implants. 1999 Jul-Aug;14(4):565-70.
8. Chen Y, Kang ST, Bae SM, Kyung HM. Clinical and histologic analysis of the stability of microimplants with immediate orthodontic loading in dogs. Am J Orthod Dentofacial Or-thop. 2009 Aug;136(2):260-7.
9. Erverdi N, Keles A, Nanda R. The use of skeletal anchorage in open bite treatment: A cephalometric evaluation. Angle Orthod. 2004 Jun; 74(3):381-90.
10. Proffit WR, Fields HW, Sarver DM. Contemporary orthodontics. 5th ed. St. louis: Mosby; 2015, 383.
11. Holm L, Cunningham SJ, Petrie A, Cousley RR. An in vitro study of factors affecting the primary stability of orthodontic mini-implants. Angle Orthod. 2012 Nov; 82(6):1022-8.
12. Zhao L, Xu Z, Yang Z, Wei X, Tang T, Zhao Z. Orthodontic mini-implant stability in different healing times before loading: a microscopic computerized tomographic and biomechanical analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Aug; 108(2):196-202.
13. Kim KH, Chung C, Yoo HM, Park DS, Jang IS, Kyung SH. The comparison of torque values in two types of mini-screws placed in rabbits: ta-pered and cylindrical shapes - Preliminary study. Korean J Orthod. 2011 Aug;41(4):280-287.
14. Nagamatsu JBT. Bone response to orthodontic mini-screw placement: An Invivo study [The-sis]. Faculty of the Graduate School, Saint Louis University; 2008.
15. Chen Y, Shin HI, Kyung HM. Biomechanical and histological comparison of self-drilling and self-tapping orthodontic microimplants in dogs. Am J Orthod Dentofacial Orthop. 2008 Jan; 133 (1):44-50.
16. Novaes AB Jr, de Souza SL, de Barros RR, Pe-reira KK, Iezzi G, Piattelli A. Influence of implant surfaces on osseointegration. Braz Dent J. 2010; 21(6):471-81.
17. Behnia H, Khoshzaban A, Zarinfar M, Mashhadi Abbas F, Bahraminasab H, Khojasteh A. Histological evaluation of regeneration in rabbit calvarial bone defects using demineral-ized bone matrix, mesenchymal stem cells and platelet rich in growth factors. J Dent Sch. 2012 Fall;30(3):143-154.
18. Gracco A, Giagnorio C, Incerti Parenti S, Alessandri Bonetti G, Siciliani G. Effects of thread shape on the pullout strength of mini-screws. Am J Orthod Dentofacial Orthop. 2012 Aug ;142(2):186-90.
19. Sakin C, Aylikci O. Techniques to measure miniscrew implant stability. J Orthodontic Res. 2013 Jul; 1(1):5-10.
20. Abd El-Fattah H, Helmy Y, El-Kholy B, Marie M. In vivo animal histomorphometric study for evaluating biocompatibility and osteointegration of nano-hydroxyapatite as biomaterials in tissue engineering. J Egypt Natl Canc Inst. 2010 Dec; 22 (4):241-50.
21. Isler SC, Cansiz E, TanyelC, Soluk M, Cebi Z. The effect of irrigation temperature on bone healing. Int J Med Sci. 2011;8(8):704-8.
22. Eriksson AR, Albrektsson T. Temperature threshold levels for heat-induced bone tissue injury: A vital-microscopic study in the rabbit. J Prosthet Dent. 1983 Jul; 50(1):101-107.
23. Eriksson RA, Albrektsson T, Magnusson B. As-sessment of bone viability after heat trauma. A histological, histochemical and vital microscop-ic study in the rabbit. Scand J Plast Reconstr Surg. 1984; 18(3):261-268.
24. Karmani S. The thermal properties of bone and the effects of surgical intervention. Curr Or-thop. 2006 Feb; 20(1):52-58.
25. Eriksson RA, Albrektsson T. The effect of heat on bone regeneration: An experimental study in the rabbit using the bone growth chamber. J Oral Maxillofac Surg. 1984 Nov;42(11):705-711.
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Araghbidi Kashani M, Jalayer Naderi N, Barande S. Histomorphometric Study of Tissue Reaction to Mini-screws with Composite Coating Implanted in the Maxilla of Rabbits. J Iran Dent Assoc 2015; 27 (4) :198-202
URL: http://jida.ir/article-1-1817-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 27, Issue 4 (10-2015) Back to browse issues page
Journal of Iranian Dental Association


This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4570