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:: Volume 31, Issue 4 (10-2019) ::
J Iran Dent Assoc 2019, 31(4): 214-217 Back to browse issues page
Salivary and Serum Ferritin Levels: Is There a Correlation?
Fatemeh Haji-Sattari1 , Mahdieh Zarabadipour * 2, Fatemeh Hajmanoochehri3 , Monirsadat Mirzadeh4
1- General Dentist, Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran
2- Assistant Professor, Department of Oral and Maxillofacial Medicine, Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Qazvin, Iran , mzarabadipour@qums.ac.ir
3- Associate Professor, Department of Pathology, Qazvin University of Medical Sciences, Qazvin, Iran
4- Assistant Professor of Community Medicine, Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
Abstract:   (1362 Views)
Background and Aim: Blood samples are used for the diagnosis of many diseases. Serum ferritin level is known to be a marker of anemia and iron overload disorders. However, blood collection is an invasive method. Saliva, as a bio-fluid, contains a va-riety of important components that are successfully used for assessment of body health. The use of saliva samples for ferritin evaluation can be regarded as a simple and noninvasive alternative to serum assessment. The aim of the present study was to evaluate the correlation between salivary and serum ferritin levels.
Materials and Methods: In this cross-sectional study, 107 participants who were re-ferred to a medical laboratory in Qazvin, Iran, voluntarily provided unstimulated sali-va and blood samples using the standard methods. The levels of ferritin in the serum and saliva samples were determined. The Spearman’s rank-order correlation coeffi-cient was used to analyze the data.
Results: The results suggested a positive correlation between the salivary and serum ferritin levels (P=0.004, r=0.27). Gender and age had no significant correlation with salivary and serum ferritin levels (P>0.05).
Conclusion: Considering the equivalent diagnostic efficacy as serum samples, salivary samples can be used as a noninvasive and simple method to determine the ferritin levels.
Keywords: Anemia, Ferritins, Saliva, Serum
Full-Text [PDF 504 kb]   (1224 Downloads)    
Type of Study: Original | Subject: Oral Medicine
References
1. Jagannathan N, Thiruvengadam C, Ramani P, Premkumar P, Natesan A, Sherlin HJ. Salivary ferritin as a predictive marker of iron deficiency anemia in children. J Clin Pediatr Dent. Fall 2012;37(1):25-30.
2. Coutinho GG, Goloni-Bertollo EM, Bertelli EC. Iron deficiency anemia in children: a challenge for public health and for society. Sao Paulo Med J. 2005 Mar;123(2):88-92.
3. Mishra OP, Agarwal KN, Agarwal RM. Salivary iron status in children with iron deficiency and iron overload. J Trop Pediatr. 1992 Apr; 38(2):64-7.
4. Allen LH. Interventions for micronutrient deficiency control in developing countries: past, present and future. J Nutr. 2003 Nov;133(11 Suppl 2):3875S-3878S.
5. Youdim MB, Yehuda S. The neurochemical basis of cognitive deficits induced by brain iron defi-ciency: involvement of dopamine-opiate sys-tem. Cell Mol Biol (Noisy-le-grand). 2000 May;46(3):491-500.
6. Sun L, Franco OH, Hu FB, Cai L, Yu Z, Li H, et al. Ferritin concentrations, metabolic syndrome, and type 2 diabetes in middle-aged and elderly Chinese. J Clin Endocrinol Metab. 2008 Dec; 93 (12):4690-6.
7. Winter WE, Bazydlo LA, Harris NS. The molecular biology of human iron metabolism. Lab Med. Spring 2014;45(2):92-102.
8. Guo LN, Yang YZ, Feng YZ. Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus. BMC Oral Health. 2018 Apr 10;18(1):63.
9. Jagannathan N, Neelakantan P, Raman P, Premkumar P, Natesan A, Sherwin H. Salivary Ferritin - A concise update on current concepts. Int J of Current Research and Review. 2012 March;4(5):58-62.
10. Haeri-Araghi H, Zarabadipour M, Safarzadeh-Khosroshahi S, Mirzadeh M. Evaluating the relationship between dental caries number and salivary level of IgA in adults. J Clin Exp Dent. 2018 Jan;10(1):e66-e69.
11. Agarwal PK, Agarwal KN, Agarwal DK. Biochemical changes in saliva of malnourished children. Am J Clin Nutr. 1984 Feb;39(2):181-184.
12. Aghazadeh M, Eslami H, Pirzadeh A, Aghazadeh Z, Dousti H, Falsafi P. Evaluation of correlation between saliva and serum ferritin level in pa-tients with Iron deficiency anemia and compari-son group. Int J Humanit Soc Sci. 2016 June;21(6):43-48.
13. Kodati S. Correlation of serum & salivary levels in iron deficiency anemia patients. Int J Biol Med Res. 2018;9(2):6317-20.
14. Rahim F. Salivary ferritin and iron as a marker and new discriminating indices between iron deficiency anemia and thalassemia: a meta-analysis. Russ Open Med J. 2017;6(2):1-6.
15. Canatan D, Akdeniz SK. Iron and ferritin levels in saliva of patients with thalassemia and iron deficiency anemia. Mediterr J Hematol Infect Dis. 2012;4(1):e2012051.
16. Navazesh M. Methods for collecting saliva. Ann N Y Acad Sci. 1993 Sep 20;694:72-7.
17. Chiappin S, Antonelli G, Gatti R, De Palo EF. Sali-va specimen: a new laboratory tool for diagnostic and basic investigation. Clin Chim Ac-ta. 2007 Sep;383(1-2):30-40.
18. Kaufman E, Lamster IB. The diagnostic applications of saliva--a review. Crit Rev Oral Biol Med. 2002 Mar;13(2):197-212.
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Haji-Sattari F, Zarabadipour M, Hajmanoochehri F, Mirzadeh M. Salivary and Serum Ferritin Levels: Is There a Correlation?. J Iran Dent Assoc 2019; 31 (4) :214-217
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Volume 31, Issue 4 (10-2019) Back to browse issues page
Journal of Iranian Dental Association

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