[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Journal Information::
Editorial Policies::
Articles archive::
For Authors::
Contact us::
Site Facilities::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Contact Us
:: Volume 26, Issue 1 (1-2014) ::
J Iran Dent Assoc 2014, 26(1): 46-49 Back to browse issues page
The Correlation of Blood Glucose with Salivary Glucose Level in Diabetic Patients
Arash Azizi * 1, Ali Modaberi2
1- Associate Professor, Department of Oral and Maxillofacial Medicine, School of Dentistry, Islamic Azad University. Tehran, Iran. , drarashazizi@yahoo.com
2- Dentist
Abstract:   (5594 Views)

Background and Aim: Finding a relationship between the blood glucose level and its concentration in other body fluids such as the saliva can help in developing a conservative method for blood sugar assessment replacing venous sampling .The aim of this study was to evaluate the relationship of blood glucose level with salivary glucose in diabetic patients .

  Materials and Methods: This case-control study was conducted on 75 diabetic patients as the case and 75 healthy subjects as the control group. Blood and salivary glucose levels were measured in the two groups. Pearson’s correlation coefficient was used to assess the correlation of blood glucose with salivary glucose in the two groups .

  Results: The mean ( ±SD) blood glucose and salivary glucose level was 247±24.2mg/dl and 1.4±0.2mg/dl in the case

  group, respectively. These rates were 84.97±15.8 and 1.09±0.12mg/dl in the control group, respectively.

  Statistical analyses showed a high correlation between blood glucose level and salivary glucose in diabetic patients (r =0/9) whereas this correlation was insignificant in the healthy control group (r = 0.18) .

  Conclusion: This study showed a high correlation between blood glucose level and salivary glucose in diabetic patients .


Keywords: Blood glucose level, Salivary glucose level, Diabetes Mellitus
Full-Text [PDF 144 kb]   (2944 Downloads)    
Type of Study: Original | Subject: Oral Medicine
1. Greenberg MS, Glick M. Burket,s oral medicine diagnosis & treatment, 11thed. Hamilton: BC Becker Co; 2008, 63-65.
2. Vasconcelos AC, Soares MS, Almeida PC, Soa-res TC. Comparative study of the concentration of salivary and blood glucose in type 2 diabetic patients. J Oral Sci. 2010 June; 52(2):293-8.
3. Little JW, Falas DA, Miller CS, Rhodus NL. Dental management of the medically compro-mised patient. 9 editions. Missouri: Mosby; 2013, 280-288.
4. Marcheti P, Tognarelli M, Giannarelli R, Grossi C, Picaro L, di Carlo A, et al. Decreased sali-vary glucose secretory rate; usefulness for de-tection of diabetic patients with autonomic neu-ropathy. Diab Res Clin Prac. 1989 Sept; 7(3):181-6.
5. Amer S, Yousuf M, Siddiqui PQ, Alam J. Salivary glucose concentration's in patient's with diabet's mellitus-A Minimally invasive tech-nique for monitoring Blood glucose levels. Pak J Pharm Sci. 2001Jan; 14(1):33-37.
6. Leach SA, Melville Th. Investigation of some human oral organisms capable of releasing the carbohydrates from salivary glycoproteins. Arch Oral Biol. 1970 Jan;15(1):87-8.
7. Ficara AJ, Levin MP, Grower MF, Cramer GD. A comparison of the glucose and protein con-tent of gingival fluid from diabetic and nondi-abetics. J Period Res. 1975 Jul; 10(3):171-5.
8. Negrato CA, Tarzia O. Buccal alteration in diabetes mellitus. Diabetol Metab Syndr. 2010 Jan; 15,2:3.
9. Reuterving CO, Reuterving G, Hagg E, Ericson T. Salivary flow rate and salivary glucose concentration in patients with diabetes mellitus influence of severity of diabetes. Diab Metabol. 1987 July-August; 13(4):457-62.
10. Chavez EM, Borell LN, Taylor GW, Ship JA. A longitudinal analysis of salivary flow in control subjects and older adults with type 2 diabetes. Oral Surgery Oral Med Oral Pathol Oral Radiol & Endod. 2001 Feb; 91(2):166-73.
11. Aydin S. A comparison of ghrelin, glucose, al-pha amylase and protein levelin saliva from di-abetics. J Biochem Mol Biol. 2007 Jan; 40(1):29-35.
12. Harrison R, Bowen WH. Flow rate and or-ganic constituents of whole saliva in insulin-dependent diabetic children and adolescents. Pediat Dent. 1987 Dec;9(4):287-291.
13. Darwazeh AMG, Macfarlane TW, McCuish A and Lamey PJ. Mixed salivary glucose levels and candidal carriage in patients with diabetes mellitus. J Oral Pathol & Med. 1991 Jul; 20(6):280-3.
14. Karjalainen KM, Knuuttila ML, Käär ML. Salivary factors in children and adolescent with insulin-dependent diabetes mellitus. Pediat Dent. 1996 Jul-Aug;18(4):306-11.
15. López ME, Colloca ME, Páez RG, Schallmach JN, Koss MA, Chervonagura A. Salivary characterestics of diabete children. Braz Dent J. 2003 June;14(1):26-31.
16. Jurysta C, Bulur N, Oguzan B, Satman I, Yilmaz Tm, et al. Salivary glucose concentra-tion and excretion in normal and diabetic sub-jects. J Biomed Biotech. 2009.
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Azizi A, Modaberi A. The Correlation of Blood Glucose with Salivary Glucose Level in Diabetic Patients. J Iran Dent Assoc 2014; 26 (1) :46-49
URL: http://jida.ir/article-1-1556-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 26, Issue 1 (1-2014) Back to browse issues page
Journal of Iranian Dental Association


This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Persian site map - English site map - Created in 0.04 seconds with 37 queries by YEKTAWEB 4652