Effect of Three Different Remineralizing Agents on White Spot 
Lesions; AnIn Vitro Comparative Study

Tahmasbi , Soodeh; Adhami , Mahya; Valian , Azam; Hamedi , Roya

doi:10.30699/jidai.29.3.98

[Home ] [Archive]

Main Menu

Journal Information

Editorial Policies

Articles archive

For Authors

Contact us

Site Facilities

Search in website

Receive site information

Last site contents
:: Contact Us

Volume 28, Issue 3 (7-2016)

J Iran Dent Assoc 2016, 28(3): 98-103

Back to browse issues page

Effect of Three Different Remineralizing Agents on White Spot Lesions; AnIn Vitro Comparative Study

Soodeh Tahmasbi¹

, Mahya Adhami²

, Azam Valian³

, Roya Hamedi ^*

⁴

1- Assistant Professor, Department of Orthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Dentist, Private Office, Tehran, Iran
3- Associate Professor, Department of Operative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Assistant Professor, Department of Orthodontics, Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Qazvin, Iran , dr.r.hamedi@gmail.com

Abstract: (3510 Views)

Background and Aim: White spot lesions (WSLs) are common occurrence following orthodontic treatment, this study sought to compare the remineralizing potential of fluoride, MI Paste Plus (CPP-ACP-F) and Remin Pro for treatment of WSLs.

Materials and Methods: This in vitro study was conducted on 56 sound human premolars that extracted for orthodontic purposes. Teeth were cleaned and their roots were cut, then the crowns were mounted in acrylic resin. Teeth surfaces were coated with nail varnish except for a 3×4mm window on the buccal surface. In order to create WSLs, all samples were immersed in demineralizing solution for 10 days. After surface hardness was measured using a Vickers microhardness tester, teeth were randomly divided into four groups. In control group (group 1) no remineralizing agent was used while, groups 2 to 4, were treated with0.05% sodium fluoride (NaF), MI Paste Plus, and Remin Pro paste respectively, for five minutes every 12hours. After each treatment, specimens were immersed in freshly prepared artificial saliva. At the end of 28 days, surface microhardness was measured again and changes were statistically analyzed using analysis of covariance (ANCOVA).
Results: The mean changes in surface microhardness of MI Paste Plus, NaF and Remin Pro groups was significantly higher than control group (P˂0.001, P˂0.001 and P0.046 respectively).
Conclusion: MI Paste Plus, 0.05% NaF mouthwash, and to a lesser extent Remin Pro were efficient for treatment of WSLs comparing to the artificial saliva.

Keywords: Dental Caries, Sodium fluoride, Mouthwashes, Therapeutics

Full-Text [PDF 226 kb] (2098 Downloads)

Type of Study: Original | Subject: Orthodontics

References

1. Sudjalim TR, Woods MG, Manton DJ, Reynolds EC. Prevention of demineralization around orthodontic brackets in vitro. Am J Orthod Dentofacial Orthop. 2007 Jun;131(6):705.e1-9.

2. Ballard RW, Hagan JL, Phaup AN, Sarkar N, Townsend JA, Armbruster PC. Evaluation of 3commercially available materials for resolution of white spot lesions. Am J Orthod Dentofacial Orthop. 2013 Apr;143(4 Suppl):S78-84.

3. Bergstrand F, Twetman S. A review on prevention and treatment of post-orthodontic white spot lesions-evidence-based methods and emerging technologies. Open Dent J. 2011;5:158-62.

4. Chen H, Liu X, Dai J, Jiang Z, Guo T, Ding Y. Effect of remineralizing agents on white spot lesions after orthodontic treatment: a systematic review. Am J Orthod Dentofacial Orthop. 2013 Mar;143(3):376-382.

5. Morrier JJ. [White spot lesions and orthodontic treatment. Prevention and treatment]. Orthod Fr. 2014 Sep;85(3):235-44.

6. Protection. Care. Conservation: Remin Pro (not available in CAN!). Available at: www.voco.com/us/product/Remin_Pro/index.html/Accessed June 1, 2015.

7. Heshmat H, Ganjkar MH, Jaberi S, Fard MJ. The effect of remin pro and MIpasteplus on bleached enamel surface roughness. J Dent (Tehran). 2014 Mar;11(2):131-6.

8. Behroozibakhsh M, Shafiei F, Hooshmand T, Moztarzadeh F, Tahriri M, Bagheri Gorgani H. Effect of a synthetic nanocrystalline-fluorohydroxyapatite on the eroded enamel lesions. Dent Mater.2014;30(Supplement 1):e117–e118.

9. Featherstone JD. Dental caries: a dynamic disease process. Aust Dent J. 2008 Sep;53(3):286-91.

10. ten Cate JM, Duijsters PP. Alternating demineralization and remineralization of artifi-cial enamel lesions. Caries Res. 1982;16(3):201-10.

11. van Dijk JW, Borggreven JM, Driessens FC. Chemical and mathematical simulation of car-ies. Caries Res. 1979;13(3):169-80.

12. Mohan AG, Ebenezar AV, Ghani MF, Martina L, Narayanan A, Mony B. Surface and mineralchanges of enamel with different remineralizing agents in conjunction with carbon-dioxidelaser. Eur J Dent. 2014 Jan; 8(1): 118-23.

13. Shetty S, Hegde MN, Bopanna TP. Enamel remineralization assessment after treatment with three different remineralizing agents using surface microhardness: An inVitro study. J Conserv Dent. 2014 Jan;17(1):49-52.

14. Lata S, Varghese NO, Varughese JM. Re-mineralization potential of fluoride and amorphous calcium phosphate case in phosphopeptide on enamel lesions: An in vitro comparative evaluation. J Conserv Dent. 2010 Jan; 13(1):42-6.

15. Vyavhare S, Sharma DS, Kulkarni VK. Effect of three different pastes on remineralization of initial enamel lesion: an in vitro study. J Clin Pediatr Dent. 2015 Winter;39(2):149-60.

16. Heshmat H, Ganjkar MH, Miri Y, Kharrazi Fard MJ. The effect of two remineral-izing agents and natural saliva on bleached enamel hardness. Dent Res J (Isfahan). 2016 Jan-Feb; 13 (1):52-7.

Send email to the article author

Add your comments about this article

‎ 10.30699/jidai.29.3.98

Mendeley

Zotero

RefWorks

Tahmasbi S, Adhami M, Valian A, Hamedi R. Effect of Three Different Remineralizing Agents on White Spot Lesions; AnIn Vitro Comparative Study . J Iran Dent Assoc 2016; 28 (3) :98-103
URL: http://jida.ir/article-1-1870-en.html

Rights and permissions
	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Volume 28, Issue 3 (7-2016)

Back to browse issues page

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Persian site map - English site map - Created in 0.05 seconds with 37 queries by YEKTAWEB 4645