Submitted: 28 Sep 2020
Accepted: 18 Oct 2019
ePublished: 18 Oct 2019
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J Iran Dent Assoc. 2019;31(4): 214-217.
  Abstract View: 20

Original

Salivary and Serum Ferritin Levels: Is There a Correlation?

Fatemeh Haji-Sattari, Mahdieh Zarabadipour* ORCID logo, Fatemeh Hajmanoochehri, Monirsadat Mirzadeh
*Corresponding Author: Email: mzarabadipour@qums.ac.ir

Abstract

Background and Aim: Blood samples are used for the diagnosis of many diseases. Serum ferritin level is known to be a marker of anemia and iron overload disorders. However, blood collection is an invasive method. Saliva, as a bio-fluid, contains a va-riety of important components that are successfully used for assessment of body health. The use of saliva samples for ferritin evaluation can be regarded as a simple and noninvasive alternative to serum assessment. The aim of the present study was to evaluate the correlation between salivary and serum ferritin levels.
Materials and Methods: In this cross-sectional study, 107 participants who were re-ferred to a medical laboratory in Qazvin, Iran, voluntarily provided unstimulated sali-va and blood samples using the standard methods. The levels of ferritin in the serum and saliva samples were determined. The Spearman’s rank-order correlation coeffi-cient was used to analyze the data.
Results: The results suggested a positive correlation between the salivary and serum ferritin levels (P=0.004, r=0.27). Gender and age had no significant correlation with salivary and serum ferritin levels (P>0.05).
Conclusion: Considering the equivalent diagnostic efficacy as serum samples, salivary samples can be used as a noninvasive and simple method to determine the ferritin levels.
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